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NEWS RELEASES - via EurekAlert!

OHIO professor Hla develops robust molecular propeller for unidirectional rotations

( Ohio University) A team of scientists from Ohio University, Argonne National Laboratory, Universitié de Toulouse in France and Nara Institute of Science and Technology in Japan led by OHIO Professor of Physics Saw-Wai Hla and Prof. Gwenael Rapenne from Toulouse developed a molecular propeller that enables unidirectional rotations on a material surface when energized.

Machine learning models help clinicians identify people who need advanced depression care

( Regenstrief Institute) Regenstrief Institute and Indiana University researchers have created decision models capable of predicting which patients might need more treatment for their depression than what their primary care provider can offer. The algorithms were specifically designed to provide information the clinician can act on and fit into existing clinical workflows.

Landos Biopharma doses first patient in global phase 2 clinical trial of BT-11 for UC

( LaVoieHealthScience) Landos Biopharma, Inc., a clinical-stage biopharmaceutical company focused on the discovery and development of therapeutics for patients with autoimmune diseases today announced dosing of the first patient in a Phase 2 study evaluating the safety and efficacy of BT-11 in patients with mild to moderate ulcerative colitis (UC). BT-11 is a novel, orally-administered, gut-restricted, first-in-class therapeutic in clinical development for UC and Crohn's disease (CD).

New hydrogels show promise in treating bone defects

( University of California - Los Angeles) Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration. Once injected in a mouse model, the new hydrogel is shown to induce migration of naturally occurring stem cells to better promote bone healing. Current experimental applications using hydrogels and stem cells introduced into the body or expensive biological agents can come with negative side effects.

Preventing privacy leaks when online data can be gathered publicly

( University of Missouri-Columbia) Rohit Chadha, an associate professor of electrical engineering and computer science in the College of Engineering at the University of Missouri, is working with researchers at the University of Illinois-Chicago and the University of Illinois Urbana-Champaign on a $1.2 million grant over 4 years from the National Science Foundation to study how to help prevent privacy leaks when there is a large amount of data that can be gathered publicly.

Skeletal shapes key to rapid recognition of objects

( Emory Health Sciences) In the blink of an eye, the human visual system can process an object, determining whether it's a cup or a sock within milliseconds, and with seemingly little effort. It's well-established that an object's shape is a critical visual cue to help the eyes and brain perform this trick. A new study, however, finds that while the outer shape of an object is important for rapid recognition, the object's inner 'skeleton' may play an even more important role.

Solution from VTT to prevent beer bottle explosions

( VTT Technical Research Centre of Finland) Some contaminant yeasts make beer bottles and cans explode. VTT scientists developed a genetic test for brewers to detect the strains that cause these problems.

A single change at telomeres controls the ability of cells to generate a complete organism

( Centro Nacional de Investigaciones Oncológicas (CNIO)) Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants. But pluripotency is still a black box for science, controlled by unknown genetic and epigenetic signals. CNIO researchers now uncovers one of those epigenetic signals, after a detective quest that started almost a decade ago.

Mini kidneys grown from stem cells give new insights into kidney disease and therapies

( Nanyang Technological University) An international team led by NTU Singapore has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients. These kidney organoids were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease. This method has paved the way for tailoring treatment plans specific to each patient, which could be extended to a range of kidney diseases.

World's thinnest, lightest signal amplifier enables bioinstrumentation with reduced noise

( Osaka University) A research group led by Professor Tsuyoshi Sekitani and Associate Professor Takafumi Uemura of The Institute of Scientific and Industrial Research, Osaka University, succeeded in developing the world's thinnest and lightest differential amplifier for bioinstrumentation.

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